21st Amendment Brewery Cafe Announces Closure and Layoffs

21st Amendment Brewery Cafe, one of the largest craft breweries in the Bay Area, is shutting down due to ongoing financial struggles, leading to the layoff of approximately 100 employees. The brewery has faced significant cash flow issues, which have ultimately resulted in its closure. The decision to cease operations was made public in early October 2023, marking the end of a notable establishment in the local craft beer scene. This closure reflects broader challenges within the craft brewing industry, but specific details about the brewery's financial difficulties were highlighted in the announcement.

LayoffTalk has tracked 4 layoff events at 21st Amendment Brewery Cafe since September 2025, including 76 jobs documented in official WARN filings, with 3 additional events known from news reporting.