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REPORTED · WARN NOTICEPublished Dec 10, 2025

Illumina, Inc. Layoff — January 2026

EMPLOYEES AFFECTED
28
SHARE OF WORKFORCE
~0.6%
EFFECTIVE DATE
Jan 5, 2026
28 OF 5,000 EMPLOYEES

What we know

Location: Illumina Way San Diego, CA (San Diego County).

A WARN notice was filed on November 6, 2025.

Disclosed through an official WARN filing with the CA state workforce agency.

Summary

Illumina, Inc. disclosed this layoff in an official WARN (Worker Adjustment and Retraining Notification) notice filed with the CA state workforce agency on November 6, 2025. The notice covers 28 employees in Illumina Way San Diego, CA (San Diego County), with the layoff effective January 5, 2026.

That is roughly 0.6% of the 5,000 people Illumina, Inc. employs.

LayoffTalk has tracked 12 layoff events at Illumina, Inc. since April 2023, affecting a combined 654 employees.

Comments (1)

Anonymous by default. Be kind — people reading this may be going through it right now.

LTLayoffTalk StaffStaff22 hours ago

Illumina, Inc. cut 28 jobs in Illumina Way San Diego, CA on January 5, 2026. Were you affected, or do you know people who were? How was it handled — severance, notice, which teams? You can post anonymously below.

SOURCE
Official WARN notice
View state filing ↗
I
Illumina, Inc.ILMN
Health Care · 5,000 employees
12
EVENTS TRACKED
654
AFFECTED SINCE 2023
View company profile+ Get alerts for Illumina, Inc.

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CREATED DEC 10, 2025LAST UPDATED DEC 10, 2025