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REPORTED · NEWSPublished Dec 26, 2025

Intercept Pharmaceuticals Restructures with 146 Layoffs Following Ocaliva Withdrawal

EMPLOYEES AFFECTED
146
SHARE OF WORKFORCE
~73%
EFFECTIVE DATE
Oct 1, 2023
146 OF 200 EMPLOYEES

What we know

Based on news reporting.

Summary

Intercept Pharmaceuticals has announced a restructuring that will result in 146 layoffs, following the withdrawal of its drug Ocaliva. This decision comes as the company seeks to realign its operations after the setback with Ocaliva, which has impacted its business strategy. The layoffs are part of a broader effort to streamline the organization and focus on future growth opportunities. The exact locations and departments affected by these layoffs have not been disclosed. This move reflects the challenges faced by Intercept in the current pharmaceutical landscape.

Intercept Pharmaceuticals cut 146 jobs as of October 1, 2023.

That is roughly 73% of the 200 people Intercept Pharmaceuticals employs.

LayoffTalk has tracked 3 layoff events at Intercept Pharmaceuticals since October 2023, affecting a combined 438 employees.

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SOURCE
News reporting
View original source ↗
I
Intercept PharmaceuticalsICPT
Health Care · 200 employees
3
EVENTS TRACKED
438
AFFECTED SINCE 2023
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CREATED DEC 26, 2025LAST UPDATED DEC 26, 2025