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REPORTED · NEWSPublished Dec 28, 2025

Pfizer Inc. Faces Layoffs Due to Disinterest in PROTAC Inhibitor

EMPLOYEES AFFECTED
200
SHARE OF WORKFORCE
~0.2%
EFFECTIVE DATE
Oct 1, 2023
200 OF 88,000 EMPLOYEES

What we know

Location: New York, NY, USA.

Department affected: Biotech Division.

Based on news reporting.

Summary

Pfizer Inc. has announced layoffs affecting approximately 200 employees in its biotech division due to a loss of interest in commercializing a PROTAC inhibitor. This decision comes as the company shifts its focus away from this specific project, which has led to a restructuring within the organization. The layoffs are expected to impact operations significantly, as the affected employees were integral to the development of this therapeutic approach. The company is navigating a challenging landscape in biotech, prompting these workforce reductions to realign its strategic priorities.

Pfizer Inc. cut 200 jobs affecting its Biotech Division team as of October 1, 2023.

That is roughly 0.2% of the 88,000 people Pfizer Inc. employs.

LayoffTalk has tracked 8 layoff events at Pfizer Inc. since October 2023, affecting a combined 618 employees.

Comments (1)

Anonymous by default. Be kind — people reading this may be going through it right now.

LTLayoffTalk StaffStaff22 hours ago

Pfizer Inc. cut 200 jobs on October 1, 2023. Were you affected, or do you know people who were? How was it handled — severance, notice, which teams? You can post anonymously below.

SOURCE
News reporting
View original source ↗
P
Pfizer Inc.PFE
Healthcare · 88,000 employees
8
EVENTS TRACKED
1,018
AFFECTED SINCE 2023
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CREATED DEC 28, 2025LAST UPDATED DEC 28, 2025