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REPORTED · NEWSPublished Sep 18, 2025

Pfizer Inc. Faces Layoffs Due to Disinterest in PROTAC Inhibitor

SOURCENews reportView the filing ↗

EFFECTIVE DATE
Sep 18, 2025

What we know

Location: New York, NY, USA.

Department affected: Biotech Division.

Based on news reporting.

Summary

Pfizer Inc. has announced layoffs affecting approximately 200 employees in its biotech division due to a loss of interest in commercializing a PROTAC inhibitor. This decision comes as the company shifts its focus away from this specific project, which has led to a restructuring within the organization. The layoffs are expected to impact operations significantly, as the affected employees were integral to the development of this therapeutic approach. The company is navigating a challenging landscape in biotech, prompting these workforce reductions to realign its strategic priorities.

LayoffTalk has tracked 9 layoff events at Pfizer Inc. since April 2023, including 404 jobs documented in official WARN filings, with 5 additional events known from news reporting.

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SOURCE
News reporting
View original source ↗
P
Pfizer Inc.PFE
Health Care · 88,000 employees
9
EVENTS TRACKED
404
JOBS IN WARN FILINGS
View company profile

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CREATED DEC 28, 2025LAST UPDATED AUG 12, 2026