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REPORTED · NEWSPublished Dec 24, 2025

Alector LLC Halves Staff Following Phase 3 Trial Failure

EMPLOYEES AFFECTED
50
EFFECTIVE DATE
Oct 1, 2023

What we know

Location: San Francisco, California, USA.

Based on news reporting.

Summary

Alector LLC has announced significant layoffs, cutting its workforce by half, which equates to approximately 50 employees. This decision follows the disappointing results of a Phase 3 clinical trial for an antibody developed in partnership with GSK aimed at treating dementia. The company is now focusing on its remaining programs and streamlining operations in light of the trial's failure. The layoffs are part of a broader effort to adjust to the challenges faced in the biotech sector, particularly in the development of new therapies. Alector's headquarters is located in San Francisco, California.

Alector LLC cut 50 jobs as of October 1, 2023.

LayoffTalk has tracked 4 layoff events at Alector LLC since October 2023, affecting a combined 364 employees.

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SOURCE
News reporting
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A
Alector LLCALEC
Health Care
4
EVENTS TRACKED
364
AFFECTED SINCE 2023
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CREATED DEC 24, 2025LAST UPDATED DEC 26, 2025