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REPORTED · WARN NOTICEPublished Dec 10, 2025

Alector LLC Layoff — December 2025

EMPLOYEES AFFECTED
75
EFFECTIVE DATE
Dec 22, 2025

What we know

Location: South San Francisco, CA (San Mateo County).

A WARN notice was filed on October 21, 2025.

Disclosed through an official WARN filing with the CA state workforce agency.

Summary

Alector LLC disclosed this layoff in an official WARN (Worker Adjustment and Retraining Notification) notice filed with the CA state workforce agency on October 21, 2025. The notice covers 75 employees in South San Francisco, CA (San Mateo County), with the layoff effective December 22, 2025.

LayoffTalk has tracked 4 layoff events at Alector LLC since October 2023, affecting a combined 364 employees.

Comments (1)

Anonymous by default. Be kind — people reading this may be going through it right now.

LTLayoffTalk StaffStaff22 hours ago

Alector LLC cut 75 jobs in South San Francisco, CA on December 22, 2025. What did this look like from the inside — which teams, how much notice, what severance was offered? You can post anonymously below.

SOURCE
Official WARN notice
View state filing ↗
A
Alector LLCALEC
Health Care
4
EVENTS TRACKED
364
AFFECTED SINCE 2023
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CREATED DEC 10, 2025LAST UPDATED DEC 10, 2025