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REPORTED · WARN NOTICEPublished Dec 10, 2025

City of Hope Layoff — November 2025

EMPLOYEES AFFECTED
56
SHARE OF WORKFORCE
~1.1%
EFFECTIVE DATE
Nov 25, 2025
56 OF 5,000 EMPLOYEES

What we know

Location: Duarte Road Duarte, CA (Los Angeles County).

A WARN notice was filed on September 25, 2025.

Disclosed through an official WARN filing with the CA state workforce agency.

Summary

City of Hope disclosed this layoff in an official WARN (Worker Adjustment and Retraining Notification) notice filed with the CA state workforce agency on September 25, 2025. The notice covers 56 employees in Duarte Road Duarte, CA (Los Angeles County), with the layoff effective November 25, 2025.

That is roughly 1.1% of the 5,000 people City of Hope employs.

LayoffTalk has tracked 3 layoff events at City of Hope since October 2023, affecting a combined 396 employees.

Comments (1)

Anonymous by default. Be kind — people reading this may be going through it right now.

LTLayoffTalk StaffStaff23 hours ago

City of Hope cut 56 jobs in Duarte Road Duarte, CA on November 25, 2025. What did this look like from the inside — which teams, how much notice, what severance was offered? You can post anonymously below.

SOURCE
Official WARN notice
View state filing ↗
C
City of Hope
Health Care · 5,000 employees
3
EVENTS TRACKED
396
AFFECTED SINCE 2023
View company profile+ Get alerts for City of Hope

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CREATED DEC 10, 2025LAST UPDATED DEC 10, 2025