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REPORTED · NEWSPublished Dec 28, 2025

Illumina Announces Workforce Reductions at San Diego Headquarters

EMPLOYEES AFFECTED
100
SHARE OF WORKFORCE
~2.0%
EFFECTIVE DATE
Oct 1, 2023
100 OF 5,000 EMPLOYEES

What we know

Location: San Diego, California.

Based on news reporting.

Summary

Illumina, Inc. has laid off approximately 100 employees at its San Diego headquarters as part of a restructuring effort aimed at streamlining operations. This decision comes amid ongoing challenges in the biotechnology sector, where the company has faced increased competition and market pressures. The layoffs are part of a broader strategy to enhance efficiency and focus on core business areas. The affected employees were notified on October 1, 2023, as the company seeks to adapt to changing market conditions and improve its financial performance.

Illumina, Inc. cut 100 jobs as of October 1, 2023.

That is roughly 2% of the 5,000 people Illumina, Inc. employs.

LayoffTalk has tracked 12 layoff events at Illumina, Inc. since April 2023, affecting a combined 654 employees.

Comments (1)

Anonymous by default. Be kind — people reading this may be going through it right now.

LTLayoffTalk StaffStaff21 hours ago

Illumina, Inc. cut 100 jobs on October 1, 2023. Were you affected, or do you know people who were? How was it handled — severance, notice, which teams? You can post anonymously below.

SOURCE
News reporting
View original source ↗
I
Illumina, Inc.ILMN
Health Care · 5,000 employees
12
EVENTS TRACKED
654
AFFECTED SINCE 2023
View company profile+ Get alerts for Illumina, Inc.

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CREATED DEC 28, 2025LAST UPDATED DEC 31, 2025