Spark Therapeutics, Inc. Layoff
SOURCEOFFICIAL FILINGPennsylvania Department of Labor and Industry· filed April 1, 2025View the filing ↗
What we know
Location: Philadelphia, PA (Philadelphia County).
A WARN notice for this layoff is recorded on April 1, 2025.
Disclosed through an official WARN filing with the PA state workforce agency.
Summary
Spark Therapeutics, a gene therapy company based in Philadelphia’s University City and owned by Roche Group, announced it is laying off 337 employees—more than half its workforce—as part of a Roche-led restructuring. The company said another 310 Spark employees will be integrated into Roche and remain in Philadelphia. Roche announced the restructuring Jan. 30 after a near-complete write-down of the $4.8 billion acquisition of Spark and cessation of development on a key hemophilia A candidate. Spark told Pennsylvania regulators that layoffs will begin in May with additional rounds in July and December; Roche expects restructuring costs at Spark to top $300 million this year. Spark said it will remain based in Philadelphia and that plans for its Gene Therapy Innovation Center are unchanged.
Spark Therapeutics, Inc. disclosed this layoff in an official WARN (Worker Adjustment and Retraining Notification) notice recorded by the PA state workforce agency on April 1, 2025. The notice covers 298 employees in Philadelphia, PA (Philadelphia County).
That is roughly 66.2% of the 450 people Spark Therapeutics, Inc. employs.
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