Sutro Biopharma, Inc. Layoff — September 2025
SOURCEOFFICIAL FILINGCalifornia Employment Development Department· filed September 29, 2025View the filing ↗
What we know
Location: Oyster Point Blvd South San Francisco, CA · 3 locations (San Mateo County).
A WARN notice for this layoff is recorded on September 29, 2025.
Disclosed through an official WARN filing with the CA state workforce agency.
Summary
Sutro Biopharma, Inc. is making deeper cuts to extend its financial runway into 2027 and to reach key data readouts. Specific details regarding the number of employees affected by these cuts were not disclosed.
Sutro Biopharma, Inc. disclosed this layoff in an official WARN (Worker Adjustment and Retraining Notification) notice recorded by the CA state workforce agency on September 29, 2025. The notice covers 54 employees in Oyster Point Blvd South San Francisco, CA (San Mateo County), with the layoff effective September 30, 2025.
The state lists each affected employee separately by work location, so this filing spans 3 CA communities: Industrial Rd San Carlos, Oyster Point Blvd South San Francisco, Remote.
That is roughly 54% of the 100 people Sutro Biopharma, Inc. employs.
LayoffTalk has tracked 6 layoff events at Sutro Biopharma, Inc. since March 2025, including 119 jobs documented in official WARN filings, with 4 additional events known from news reporting.
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