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REPORTED · WARN NOTICEPublished Dec 10, 2025

Sutro Biopharma, Inc. Layoff — September 2025

EMPLOYEES AFFECTED
8
SHARE OF WORKFORCE
~8.0%
EFFECTIVE DATE
Sep 30, 2025
8 OF 100 EMPLOYEES

What we know

Location: Industrial Rd San Carlos, CA (San Mateo County).

A WARN notice was filed on September 29, 2025.

Disclosed through an official WARN filing with the CA state workforce agency.

Summary

Sutro Biopharma, Inc. has experienced its second round of layoffs this year, resulting in a loss of one-third of its workforce. The company is undergoing significant restructuring as part of its efforts to streamline operations.

Sutro Biopharma, Inc. disclosed this layoff in an official WARN (Worker Adjustment and Retraining Notification) notice filed with the CA state workforce agency on September 29, 2025. The notice covers 8 employees in Industrial Rd San Carlos, CA (San Mateo County), with the layoff effective September 30, 2025.

That is roughly 8% of the 100 people Sutro Biopharma, Inc. employs.

LayoffTalk has tracked 7 layoff events at Sutro Biopharma, Inc. since October 2023, affecting a combined 340 employees.

Comments (1)

Anonymous by default. Be kind — people reading this may be going through it right now.

LTLayoffTalk StaffStaff22 hours ago

Sutro Biopharma, Inc. cut 8 jobs in Industrial Rd San Carlos, CA on September 30, 2025. If you were part of this round, what was your experience? Others going through it are reading. You can post anonymously below.

SOURCE
Official WARN notice
View state filing ↗
S
Sutro Biopharma, Inc.STRO
Health Care · 100 employees
7
EVENTS TRACKED
340
AFFECTED SINCE 2023
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CREATED DEC 10, 2025LAST UPDATED DEC 30, 2025