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REPORTED · NEWSPublished Dec 28, 2025

Genentech, Inc. Implements Third Round of Layoffs in 15 Months

EMPLOYEES AFFECTED
300
SHARE OF WORKFORCE
~2.3%
EFFECTIVE DATE
Oct 1, 2023
300 OF 13,000 EMPLOYEES

What we know

Location: South San Francisco, CA.

Based on news reporting.

Summary

Genentech, Inc., the Bay Area's oldest biotech company, has announced its third round of layoffs in the past 15 months, affecting approximately 300 employees. This decision comes as part of ongoing restructuring efforts aimed at streamlining operations and adapting to changing market conditions. The layoffs are set to take place in South San Francisco, CA, and reflect the company's response to economic pressures and the need for efficiency. Genentech has faced challenges in recent years, prompting these workforce reductions as it seeks to maintain its competitive edge in the biotech industry.

Genentech, Inc. cut 300 jobs as of October 1, 2023.

That is roughly 2.3% of the 13,000 people Genentech, Inc. employs.

LayoffTalk has tracked 15 layoff events at Genentech, Inc. since October 2023, affecting a combined 1,851 employees.

Comments (1)

Anonymous by default. Be kind — people reading this may be going through it right now.

LTLayoffTalk StaffStaff21 hours ago

Genentech, Inc. cut 300 jobs on October 1, 2023. What did this look like from the inside — which teams, how much notice, what severance was offered? You can post anonymously below.

SOURCE
News reporting
View original source ↗
G
Genentech, Inc.RHHBY
Health Care · 13,000 employees
15
EVENTS TRACKED
1,951
AFFECTED SINCE 2023
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CREATED DEC 28, 2025LAST UPDATED DEC 28, 2025