REPORTED · WARN NOTICE✓ VERIFIEDAdded Jul 3, 2026

Genentech, Inc. Layoff — July 2026

SOURCEOFFICIAL FILINGCalifornia Employment Development Department· filed June 26, 2026View the filing ↗

EMPLOYEES AFFECTED

103

SHARE OF WORKFORCE

~0.8%

EFFECTIVE DATE

Jul 29, 2026

103 OF 13,000 EMPLOYEES

What we know

Location: California, USA (San Mateo County).

Department affected: research and early development (gRED) and several areas.

A WARN notice for this layoff is recorded on June 26, 2026.

Disclosed through an official WARN filing with the CA state workforce agency.

Summary

Roche’s Genentech will lay off 103 employees in California by the end of the month, according to a California WARN report, part of ongoing restructuring that has totaled nearly 450 California layoffs in the past year. The cuts will affect roles across several areas, including the company’s research and early development group (gRED). Genentech framed the reductions as focused organizational adjustments to align capabilities and investments with core therapeutic areas while continuing to hire in some areas. The announcement accompanied a separate collaboration with Astex Pharmaceuticals and follows prior disclosed eliminations such as 141 roles earlier in the year and other R&D reductions.

Genentech, Inc. disclosed this layoff in an official WARN (Worker Adjustment and Retraining Notification) notice recorded by the CA state workforce agency on June 26, 2026. The notice covers 103 employees in DNA Way South San Francisco, CA (San Mateo County), with the layoff effective July 29, 2026.

That is roughly 0.8% of the 13,000 people Genentech, Inc. employs.

LayoffTalk has tracked 13 layoff events at Genentech, Inc. since May 2023, including 1,392 jobs documented in official WARN filings, with 5 additional events known from news reporting.