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REPORTED · WARN NOTICEPublished Dec 10, 2025

Genentech, Inc. Layoff — September 2025

EMPLOYEES AFFECTED
87
SHARE OF WORKFORCE
~0.7%
EFFECTIVE DATE
Sep 15, 2025
87 OF 13,000 EMPLOYEES

What we know

Location: DNA Way South San Francisco, CA (San Mateo County).

A WARN notice was filed on July 16, 2025.

Disclosed through an official WARN filing with the CA state workforce agency.

Summary

Genentech, Inc. disclosed this layoff in an official WARN (Worker Adjustment and Retraining Notification) notice filed with the CA state workforce agency on July 16, 2025. The notice covers 87 employees in DNA Way South San Francisco, CA (San Mateo County), with the layoff effective September 15, 2025.

That is roughly 0.7% of the 13,000 people Genentech, Inc. employs.

LayoffTalk has tracked 15 layoff events at Genentech, Inc. since October 2023, affecting a combined 1,851 employees.

Comments (1)

Anonymous by default. Be kind — people reading this may be going through it right now.

LTLayoffTalk StaffStaff23 hours ago

Genentech, Inc. cut 87 jobs in DNA Way South San Francisco, CA on September 15, 2025. Were you affected, or do you know people who were? How was it handled — severance, notice, which teams? You can post anonymously below.

SOURCE
Official WARN notice
View state filing ↗
G
Genentech, Inc.RHHBY
Health Care · 13,000 employees
15
EVENTS TRACKED
1,951
AFFECTED SINCE 2023
View company profile+ Get alerts for Genentech, Inc.

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CREATED DEC 10, 2025LAST UPDATED DEC 10, 2025