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REPORTED · NEWSPublished Dec 30, 2025

Genentech Lays Off 143 Employees in South San Francisco Reshuffle

EMPLOYEES AFFECTED
143
SHARE OF WORKFORCE
~1.1%
EFFECTIVE DATE
Oct 1, 2023
143 OF 13,000 EMPLOYEES

What we know

Location: South San Francisco, CA.

Based on news reporting.

Summary

Genentech, Inc. has laid off 143 employees as part of a restructuring effort in South San Francisco. This decision reflects the company's ongoing adjustments to its workforce amidst changing operational needs. The layoffs are part of a broader strategy to streamline operations and improve efficiency. The affected employees were notified of their termination on October 1, 2023. This move highlights the challenges faced by the biotech industry in adapting to market demands and maintaining competitiveness.

Genentech, Inc. cut 143 jobs as of October 1, 2023.

That is roughly 1.1% of the 13,000 people Genentech, Inc. employs.

LayoffTalk has tracked 15 layoff events at Genentech, Inc. since October 2023, affecting a combined 1,851 employees.

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SOURCE
News reporting
View original source ↗
G
Genentech, Inc.RHHBY
Health Care · 13,000 employees
15
EVENTS TRACKED
1,951
AFFECTED SINCE 2023
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CREATED DEC 30, 2025LAST UPDATED DEC 30, 2025