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REPORTED · NEWSPublished Dec 23, 2025

Genentech Cuts 118 Jobs at Headquarters in Third Layoff Round of the Year

EMPLOYEES AFFECTED
118
SHARE OF WORKFORCE
~0.9%
EFFECTIVE DATE
Oct 1, 2023
118 OF 13,000 EMPLOYEES

What we know

Location: South San Francisco, California, USA.

Based on news reporting.

Summary

Genentech, a subsidiary of Roche, has laid off 118 employees at its headquarters in South San Francisco, marking the third round of layoffs this year. This decision reflects ongoing restructuring efforts within the company as it adapts to changing market conditions. The layoffs are part of a broader strategy to streamline operations and improve efficiency. Genentech has faced challenges in recent months, prompting these workforce reductions to align with its business objectives. The company aims to maintain its competitive edge while navigating the evolving pharmaceutical landscape.

Genentech, Inc. cut 118 jobs as of October 1, 2023.

That is roughly 0.9% of the 13,000 people Genentech, Inc. employs.

LayoffTalk has tracked 15 layoff events at Genentech, Inc. since October 2023, affecting a combined 1,851 employees.

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SOURCE
News reporting
View original source ↗
G
Genentech, Inc.RHHBY
Health Care · 13,000 employees
15
EVENTS TRACKED
1,951
AFFECTED SINCE 2023
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CREATED DEC 23, 2025LAST UPDATED DEC 28, 2025