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REPORTED · NEWSPublished Dec 26, 2025

Sutro Biopharma Halves Workforce Amid Leadership Changes

EMPLOYEES AFFECTED
50
SHARE OF WORKFORCE
~50%
EFFECTIVE DATE
Oct 1, 2023
50 OF 100 EMPLOYEES

What we know

Based on news reporting.

Summary

Sutro Biopharma, Inc. has announced significant layoffs, cutting its workforce by half, which translates to approximately 50 employees. This decision comes alongside the departure of its CEO and the discontinuation of its lead antibody-drug conjugate (ADC) program. The company is undergoing a restructuring process to streamline operations and focus on its core projects. The layoffs reflect Sutro's strategic shift in response to current market conditions and internal assessments of its business direction. This move is part of a broader trend in the biotech industry as companies reassess their workforce amid economic challenges.

Sutro Biopharma, Inc. cut 50 jobs as of October 1, 2023.

That is roughly 50% of the 100 people Sutro Biopharma, Inc. employs.

LayoffTalk has tracked 7 layoff events at Sutro Biopharma, Inc. since October 2023, affecting a combined 340 employees.

Comments (1)

Anonymous by default. Be kind — people reading this may be going through it right now.

LTLayoffTalk StaffStaff21 hours ago

Sutro Biopharma, Inc. cut 50 jobs on October 1, 2023. What did this look like from the inside — which teams, how much notice, what severance was offered? You can post anonymously below.

SOURCE
News reporting
View original source ↗
S
Sutro Biopharma, Inc.STRO
Health Care · 100 employees
7
EVENTS TRACKED
340
AFFECTED SINCE 2023
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CREATED DEC 26, 2025LAST UPDATED DEC 30, 2025